CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1454
Family Name Vascular endothelial growth factor receptor 2 ligand indolyl quinolinone deriv. 12 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00323702 Functional Category Bioactive
Superfamily Beta-lactamase and Cyclin-dependent kinase 4 Binder Superfamily
Class Class 3371

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 6 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Renin inhibitor SureCN1144364 family 3 15
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Coagulation factor VII and Tissue factor inhibitor AGN-PC-00R9... 2 10
Transient receptor potential cation channel subfamily V member... 1 5
Beta-2 adrenergic receptor ligand SureCN5346426 family 8 0
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Coagulation factor X and Prothrombin inhibitor SureCN6434488 f... 3 13
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Coagulation factor VII and Tissue factor inhibitor 5-azaindole... 4 3
Coagulation factor VII and Tissue factor inhibitor 5-azaindole... 1 0
Kinesin-like protein KIF11 inhibitor AGN-PC-07R5ZC family 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00323702 CHEMBL117052 Bioactive indolyl quinolinone deriv. 12
CFAMM00323708 CHEMBL119552 Bioactive indolyl quinolinone deriv. 11
CFAMM00323705 CHEMBL324489 Bioactive indolyl quinolinone deriv. 10
CFAMM00323703 CHEMBL325003 Bioactive indolyl quinolinone deriv. 13

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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