CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14550
Family Name Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibitor Oxindole-Based Inhibitor 61 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00429001 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclin-dependent kinase 2 Binder Superfamily 2
Class Class 8

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 9 Ligand Vercirnon Family 1 1
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Prelamin-A/C and Pyruvate kinase PKM inhibitor CHEMBL1481187 f... 1 7
Cathepsin L1 and Cathepsin S inhibitor N-[(2S)-4-methyl-1-oxo-... 2 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 0
B1 bradykinin receptor ligand AGN-PC-00RZQU family 2 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-075DUF family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429001 CHEMBL271953 Bioactive Oxindole-Based Inhibitor 61
CFAMM00428999 CHEMBL272165 Bioactive GW300657X

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46420 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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