CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14559
Family Name Pol polyprotein inhibitor Palinavir deriv. 13 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00429038 Functional Category Bioactive
Superfamily Caspase-3 and Caspase-7 Binder Superfamily 4
Class Class 2449

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
HIV-1 protease Inhibitor Atazanavir Family 16 58
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Renin Inhibitor Enalkiren Family 56 44
Chymase Inhibitor NK3201 Family 1 0
Plasmepsin-2 Inhibitor KNI-10526 Family 8 10
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[... 3 0
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Renin and Pepsin A inhibitor [(2S)-1-[[(2R)-1-[[(2S,3R)-1-cycl... 2 2
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpy... 2 3
Pol polyprotein and Protease inhibitor Palinavir family 1 0
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Pol polyprotein inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-... 7 3
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 4
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-2-(benzenesulfo... 3 0
Beta-secretase 1 and Cathepsin D inhibitor N-[(2S,3R)-4-[[(4S)... 34 23
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 3 1
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Pol polyprotein and Cytochrome P450 3A4 inhibitor (2S)-4-(3a,6... 2 0
Pol polyprotein inhibitor (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3S)... 1 0
Renin inhibitor SureCN7300793 family 2 5
Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-met... 1 1
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429038 CHEMBL272599 Bioactive Palinavir deriv. 13

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543