CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14568
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Serine/threonine-protein kinase mTOR inhibitor [(1S,3aR,6E,9S,9aR,10R,11aS)-6-[[2-(dimethylamino)ethyl-ethylamino]methylidene]-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate family
No. of Seeds 4 No. of Other Members 26
Family Centroid CFAMM00429083 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor PX-866 Superfamily
Class Class 1155

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429058 CHEMBL272816 Bioactive [(1S,3aR,6E,9S,9aR,10R,11aS)-6-[[tert-butyl-[3-(dimethylamino)propyl]amino]methylidene]-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate
CFAMM00429070 CHEMBL409427 Bioactive [(1S,3aR,6E,9S,9aR,10R,11aS)-6-[[2-(dimethylamino)ethyl-methylamino]methylidene]-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate
CFAMM00429083 CHEMBL272898 Bioactive [(1S,3aR,6E,9S,9aR,10R,11aS)-6-[[2-(dimethylamino)ethyl-ethylamino]methylidene]-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate
CFAMM00429076 CHEMBL407214 Bioactive [(1S,3aR,6E,9S,9aR,10R,11aS)-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-6-[[methyl-[3-(4-methylpiperazin-1-yl)propyl]amino]methylidene]-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

60055 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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