CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14569
Family Name Tyrosine-protein kinase Lck and Mitogen-activated protein kinase 14 inhibitor Aminopyrimidine amide, 22 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00362649 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Tyrosine-protein kinase Lck Binder Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 5 12
MK-6096 family 3 69
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Aurora kinase B and Aurora kinase A inhibitor 2-fluoro-6-metho... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 3 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429085 CHEMBL409734 Bioactive Aminopyrimidine amide, 17

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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