CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14578
Family Name Macrophage colony-stimulating factor 1 receptor and Receptor-type tyrosine-protein kinase FLT3 ligand 4-(4-ethylphenyl)-3-(2-methyl-1H-imidazol-5-yl)-2-oxo-1H-quinoline-6-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00323643 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole Analogue Superfamily
Class Class 930

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Histamine H3 receptor Ligand SCH79687 Family 11 29
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 28 9
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Coagulation factor X inhibitor SureCN8289965 family 4 5
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 10 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Serine/threonine-protein kinase Chk1 inhibitor CHIR-124 family 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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