CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14598
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand AGN-PC-02KB0T family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00429208 Functional Category Bioactive
Superfamily cAMP and Prelamin-A/C Binder Superfamily
Class Class 3083

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family 6 88
5-hydroxytryptamine receptor 6 ligand AGN-PC-031XQS family 1 1
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Adenosine kinase inhibitor SureCN8183719 family 2 3
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Type-1 angiotensin II receptor and Peroxisome proliferator-act... 6 0
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 10 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor AGN-P... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429210 CHEMBL58156 Bioactive SureCN7386457
CFAMM00429208 CHEMBL274626 Bioactive AGN-PC-02KB0T

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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