CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14606
Family Name Kappa-type opioid receptor and Mu-type opioid receptor ligand 3-(2,5-dimethoxyphenyl)-1-[2-(3-hydroxypyrrolidin-1-yl)-1-phenylethyl]pyridin-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00429230 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Lethal factor Binder Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Elagolix family 43 98
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 4
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Histamine H3 receptor ligand 4-[[2-[2-[(2R)-2-methylpyrrolidin... 1 1
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Kappa-type opioid receptor ligand N-[(1S)-2-[(3S)-3-hydroxypyr... 2 0
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429230 CHEMBL275176 Bioactive 3-(2,5-dimethoxyphenyl)-1-[2-(3-hydroxypyrrolidin-1-yl)-1-phenylethyl]pyridin-2-one
CFAMM00429231 CHEMBL64197 Bioactive AGN-PC-074C2P

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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