CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14620
Family Name Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[1-[[1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide family
No. of Seeds 6 No. of Other Members 15
Family Centroid CFAMM00429368 Functional Category Bioactive
Superfamily Furin and Trypsin-1 Binder Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 9 19
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
Telomerase reverse transcriptase Inhibitor 2,7-bis[2-(piperidi... 6 8
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
Melanocortin receptor 5 and Melanocyte-stimulating hormone rec... 3 23
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
ALK tyrosine kinase receptor and Leukocyte tyrosine kinase rec... 12 2
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-[[(2-hydroxy... 6 2
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-(piperidin-1... 10 7
C-C chemokine receptor type 3 ligand 1-(3-acetylphenyl)-3-[3-[... 9 1
Phospholipase D1 and Phospholipase D2 inhibitor 4-bromo-N-[(2S... 1 2
Neurotensin receptor type 1 ligand (2S)-2-[[(2S,3S)-2-[[(2S)-2... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR f... 5 8
Atrial natriuretic peptide receptor 1 and Atrial natriuretic p... 3 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN75047... 4 2
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429364 CHEMBL385971 Bioactive AGN-PC-075Q7Q
CFAMM00429370 CHEMBL46869 Bioactive (2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-3-[4-(diaminomethylideneamino)phenyl]-2-[[(2S)-3-(4-fluorophenyl)-2-[[(E)-3-phenylprop-2-enoyl]amino]propanoyl]amino]propanoyl]amino]-4-methylpentanamide
CFAMM00429363 CHEMBL410988 Bioactive AGN-PC-075Q6X
CFAMM00429362 CHEMBL344137 Bioactive 2-[[2-[[2-[acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[5-(diaminomethylideneamino)-1-[(1,5-diamino-1-oxopentan-2-yl)amino]-1-oxopentan-2-yl]-4-methylpentanamide
CFAMM00429368 CHEMBL276037 Bioactive 2-[[2-[[2-[acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[1-[[1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
CFAMM00429366 CHEMBL342791 Bioactive 2-[[2-[[2-[acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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