CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1463
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand SureCN2975486 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00323854 Functional Category Bioactive
Superfamily Histamine H3 receptor and Beta-1 adrenergic receptor Binder Superfamily
Class Class 1652

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histamine H3 receptor ligand SureCN3057575 family 4 3
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 7
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 10 13
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 2 1
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00323850 CHEMBL1171886 Bioactive SureCN2974769
CFAMM00323848 CHEMBL1171936 Bioactive SureCN2977123
CFAMM00323854 CHEMBL1171002 Bioactive SureCN2975486

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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