CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14641
Family Name 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine receptor 1D ligand 4-bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methylbenzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00179147 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor Binder Superfamily 4
Class Class 2835

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Transient receptor potential cation channel subfamily V member... 1 0
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
C-C chemokine receptor type 1 ligand SureCN3164653 family 2 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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