CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14642
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor AGN-PC-073HPX family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00429491 Functional Category Bioactive
Superfamily Histamine H3 receptor and Sodium-dependent dopamine transporter Binder Superfamily
Class Class 2572

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor Ligand A-349821 Family 49 228
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Histamine H1 receptor ligand Ahr 5333 family 1 6
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 3 0
Estrogen receptor and Estrogen receptor beta ligand SureCN1450... 1 1
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Estrogen receptor beta and Estrogen receptor ligand AGN-PC-074... 5 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Histamine H1 receptor and 5-hydroxytryptamine receptor 2C liga... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Multidrug resistance protein 1 inhibitor 1-[4-[(2R)-2-hydroxy-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429491 CHEMBL27748 Bioactive AGN-PC-073HPX

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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