CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1467
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 2-[2-[4-(1H-indazol-3-yl)piperazin-1-yl]ethylamino]-1H-quinazolin-4-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00323900 Functional Category Bioactive
Superfamily Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Superfamily
Class Class 1152

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Aurora kinase A inhibitor SureCN3894803 family 5 8
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 1 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-04VNKY family 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00323900 CHEMBL1171304 Bioactive 2-[2-[4-(1H-indazol-3-yl)piperazin-1-yl]ethylamino]-1H-quinazolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27521 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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