CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14688
Family Name Delta-type opioid receptor and Kappa-type opioid receptor ligand 4-(N-[8-[(Z)-but-2-enyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-methoxyanilino)-N,N-diethylbenzamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00429696 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Delta-type opioid receptor Binder Superfamily 7
Class Class 418

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
D(2) dopamine receptor Ligand Nemonapride Family 70 283
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Cinitapride family 4 22
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethyl... 1 4
Trace amine-associated receptor 1 ligand EPPTB family 4 9
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor N-[(1S,5aR,9... 2 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 15 6
Histamine H3 receptor ligand SureCN2785624 family 2 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Mu-type opioid receptor ligand AGN-PC-075GG7 family 4 2
Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family 2 0
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Motilin receptor ligand SureCN14564469 family 1 6
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[4-(3-methoxyp... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Dual specificity mitogen-activated protein kinase kinase 1 inh... 3 0
NP (s)-3-(2,5-dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepi... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429696 CHEMBL280698 Bioactive 4-(N-[8-[(Z)-but-2-enyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-methoxyanilino)-N,N-diethylbenzamide
CFAMM00429697 CHEMBL282013 Bioactive AGN-PC-076HXD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23724 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543