CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14690
Family Name Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ligand Wy-26392 family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00369497 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 5
Class Class 4371

Cousin Family NamesSeedsMembers
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Zicronapine family 43 62
Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 10
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
Sigma non-opioid intracellular receptor 1 ligand CHEMBL101300 ... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 7
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
5-hydroxytryptamine receptor 7 and Sodium-dependent serotonin ... 5 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Histamine H3 receptor and Acetylcholinesterase ligand 1-[4-[[4... 1 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
5-hydroxytryptamine receptor 1A ligand SureCN8901985 family 1 0
Histamine H3 receptor ligand 2-benzyl-4-[4-(2-pyrrolidin-1-yle... 8 4
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0
Histamine H3 receptor ligand 1-[4-[4-(pyrrolidin-1-ylmethyl)ph... 4 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Melanocortin receptor 4 ligand 1-[3-[2-(4-tert-butylphenyl)phe... 1 3
C-C chemokine receptor type 5 ligand AC1LAKMT family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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