CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14693
Family Name Substance-K receptor and Neuromedin-K receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-[3-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)propyl]piperidin-2-one family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00386544 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Prothrombin Binder Superfamily
Class Class 3482

Cousin Family NamesSeedsMembers
Growth hormone receptor Ligand Ibutamoren Family 7 41
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Prothrombin and Coagulation factor X inhibitor (2S)-N-[(4-amin... 2 3
E3 ubiquitin-protein ligase Mdm2 inhibitor (2'R,3R,3'S,5'S)-6-... 17 51
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 ligand tert-butyl 4-[(3S)-4-[4-[2-[1-[... 2 6
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 6
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 5 37
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Neuropeptide Y receptor type 5 ligand 2-(6-chloro-3,4-dihydro-... 5 1
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 3 0
Growth hormone secretagogue receptor type 1 ligand N-[4,6-dich... 2 0
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
5-hydroxytryptamine receptor 7 ligand 7-chloro-3-[4-[4-(4-chlo... 2 0
Neuromedin-K receptor and Substance-K receptor ligand AGN-PC-0... 2 2
Glutamate receptor ionotropic, NMDA 1 ligand CHEMBL40730 family 4 1
Substance-P receptor ligand N-[2-[4-[(2S)-2-(benzylamino)-3-[(... 2 0
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Aldose reductase inhibitor Spiro-cimqat family 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429743 CHEMBL54602 Bioactive AGN-PC-073SR3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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