CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14696
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor SureCN7053881 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00259798 Functional Category Bioactive
Superfamily Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta Binder Superfamily
Class Class 177

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
Histamine H3 receptor Ligand SCH79687 Family 11 29
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 1
Protein farnesyltransferase alpha subunit and Protein farnesyl... 5 0
Dipeptidyl peptidase 4 inhibitor 7-(aminomethyl)-6-(2-chloroph... 2 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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