CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14714
Family Name Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00429877 Functional Category Bioactive
Superfamily Substance-P receptor Ligand GSK424887 Superfamily
Class Class 980

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Mitogen-activated protein kinase 1 and Nonstructural protein 1... 1 33
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 3 14
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429875 CHEMBL283276 Bioactive (2R)-2-[[5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoyl]-methylamino]-3-(1H-indol-3-yl)propanoic acid
CFAMM00429877 CHEMBL281559 Bioactive (2R)-2-[[5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48694 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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