CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14725
Family Name Androgen receptor and Estrogen receptor ligand estradiol benzoate family
No. of Seeds 1 No. of Other Members 29
Family Centroid CFAMM00429919 Functional Category Bioactive with Natural Product
Superfamily Aldo-keto reductase family 1 member C3 and Steryl-sulfatase Binder Superfamily
Class Class 2073

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor Ligand Mestranol Family 2 29
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Free fatty acid receptor 1 Ligand TAK-875 Family 2 54
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Endothelin-1 receptor Ligand PD156707 Family 41 211
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
DNA polymerase Inhibitor 3alpha-o-trans-p-coumaroyl-7-labden-1... 1 13
DNA polymerase Inhibitor 3-cis-p-coumaroyl Maslinic Acid Family 3 38
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Glucocorticoid receptor ligand (4R)-4-[(3S,5R,7R,8R,9S,10S,12S... 4 12
Free fatty acid receptor 1 ligand 3-[4-[[3-[4-(1,1-dioxothian-... 3 0
Peroxisome proliferator-activated receptor delta ligand SureCN... 1 0
Glucocorticoid receptor ligand (8S,11R,13S,14S,17S)-17-hydroxy... 3 8
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Progesterone receptor and Glucocorticoid receptor ligand (8S,1... 6 1
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7
Bile acid receptor ligand benzyl (1R,3aS,5aR,5bR,7aR,9S,11aR,1... 1 21
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-benzyl-3,17-... 1 1
Steroid hormone receptor ERR1 and Steroid hormone receptor ERR... 1 0
Aldo-keto reductase family 1 member C3 inhibitor (2R,8'R,9'S,1... 1 0
Tyrosine-protein phosphatase non-receptor type 1 and Tyrosine-... 2 12
Steryl-sulfatase inhibitor [(8R,9S,13S,14S)-13-methyl-17-oxo-7... 1 9
Aromatase inhibitor [(8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo... 2 10
Aromatase inhibitor AGN-PC-075LLF family 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 2 and Corticoster... 1 2
Putative NP ZINC31158464 Family 3 5
Putative NP ZINC03881930 Family 8 5
NP 4-(5-fluoro-3-methylbenzofuran-2-yl)-7,8-dihydrocyclopenta[... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429919 CHEMBL282575 Bioactive estradiol benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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