CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14727
Family Name Protein kinase C alpha type and Protein kinase C delta type inhibitor SureCN9085019 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00429945 Functional Category Bioactive
Superfamily NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Superfamily
Class Class 929

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Serine/threonine-protein kinase Chk1 Inhibitor BIS-IMIDE A Family 1 3
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Substance-K receptor ligand 1-N,2-N-bis[2-(1H-indol-3-yl)ethyl... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family 1 2
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0
Wee1-like protein kinase inhibitor 4-(2-chlorophenyl)-9,9-dihy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429945 CHEMBL282805 Bioactive SureCN9085019
CFAMM00429946 CHEMBL285613 Bioactive AGN-PC-073GB6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26233 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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