CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14730
Family Name Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-3-thiophen-2-ylpropanamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00429966 Functional Category Bioactive
Superfamily Bone morphogenetic protein 1 and Stromelysin-1 Binder Superfamily
Class Class 3248

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 0
Bone morphogenetic protein 1 inhibitor 9H-fluoren-9-ylmethyl N... 1 24
Bone morphogenetic protein 1 inhibitor benzyl N-[(4R)-4-[1,3-b... 6 25
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 3
Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol... 1 6
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Coagulation factor X and Prothrombin inhibitor (3S)-N-(1,3-ben... 1 1
Bone morphogenetic protein 1 inhibitor (2R)-2-[(4-bromophenyl)... 1 4


External ID

Functional Category

Molecule Name

CFAMM00429968 CHEMBL92923 Bioactive 2-(1,3-benzodioxol-5-ylmethylamino)-N-hydroxy-2-methyl-3-(4-phenoxyphenyl)sulfonylpropanamide
CFAMM00429966 CHEMBL282896 Bioactive (2R)-2-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-3-thiophen-2-ylpropanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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