CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14733
Family Name Cationic trypsin and Prothrombin inhibitor (3S,6S)-6-amino-6-benzyl-N-[(3S)-6-(diaminomethylideneamino)-1,2-dioxo-1-(2-phenylethylamino)hexan-3-yl]-1,2,3,5,7,8-hexahydropyrazolo[1,2-a]pyridazine-3-carboxamide family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00429975 Functional Category Bioactive
Superfamily Prothrombin Inhibitor Ppack Superfamily
Class Class 1354

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Prothrombin Inhibitor Efegatran Family 9 47
Prothrombin Inhibitor Ppack Family 5 4
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Melanocortin receptor 4 and Substance-K receptor Ligand Hoo-ph... 3 19
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Prothrombin inhibitor SureCN7341151 family 6 7
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
NS3 and Neutrophil elastase inhibitor (2S)-3-[(2S)-2-(tert-but... 1 3
Menin inhibitor CHEMBL2314816 family 2 6
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Prothrombin and Coagulation factor VII inhibitor (3S,6S)-6-ami... 1 0
Genome polyprotein inhibitor Benzoyl-KKR-H family 1 1
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047569... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00429978 CHEMBL284549 Bioactive AC1L9FT7
CFAMM00429977 CHEMBL28365 Bioactive (3S,6S)-6-amino-6-benzyl-N-[(3S)-1-(benzylamino)-6-(diaminomethylideneamino)-1,2-dioxohexan-3-yl]-1,2,3,5,7,8-hexahydropyrazolo[1,2-a]pyridazine-3-carboxamide
CFAMM00429976 CHEMBL283022 Bioactive (3S,6S)-6-amino-6-benzyl-N-[(3S)-1-[2-(4-chlorophenyl)ethylamino]-6-(diaminomethylideneamino)-1,2-dioxohexan-3-yl]-1,2,3,5,7,8-hexahydropyrazolo[1,2-a]pyridazine-3-carboxamide
CFAMM00429975 CHEMBL28817 Bioactive (3S,6S)-6-amino-6-benzyl-N-[(3S)-6-(diaminomethylideneamino)-1,2-dioxo-1-(2-phenylethylamino)hexan-3-yl]-1,2,3,5,7,8-hexahydropyrazolo[1,2-a]pyridazine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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