CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14754
Family Name Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00430110 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 28
Class Class 1675

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Thymidylate synthase Inhibitor Leucovorin/5-fluorouracil Family 9 83
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Integrin beta-3 Inhibitor L-750034 Family 7 38
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5878245 f... 6 14
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(3-acetylphenyl)-... 1 3
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-[[(2-hydroxy... 6 2
C-C chemokine receptor type 3 ligand 1-(3-acetylphenyl)-3-[3-[... 9 1
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7502133 f... 4 7
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7102231 f... 3 8
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7503065 f... 4 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-073KEE f... 4 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7500077 f... 6 2
Integrin beta-3 and Integrin alpha-V inhibitor 3-[[[3-(diamino... 5 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-[2-[... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-[[(2S)... 1 1
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5878455 f... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430107 CHEMBL431496 Bioactive AGN-PC-02X9FD
CFAMM00430105 CHEMBL37674 Bioactive SureCN7456073
CFAMM00430104 CHEMBL417138 Bioactive AGN-PC-037CNO
CFAMM00430110 CHEMBL284274 Bioactive AGN-PC-037CNR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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