CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1476
Family Name Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-piperidine]-3-yl]ethanol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00324032 Functional Category Bioactive
Superfamily Biogenic amine receptor ligand Terfenadine Trihexyphenidyl Superfamily
Class Class 89

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Terfenadine Family 3 50
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-076TWX... 8 5
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Sigma non-opioid intracellular receptor 1 ligand SureCN7425449... 2 0
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324033 CHEMBL1172685 Bioactive 2-[(3S)-1'-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-piperidine]-3-yl]ethanol
CFAMM00324032 CHEMBL1171865 Bioactive 2-[(3R)-1'-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-piperidine]-3-yl]ethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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