CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1477
Family Name Sigma non-opioid intracellular receptor 1 ligand AGN-PC-076TWX family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00324034 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 Binder Superfamily 2
Class Class 3376

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Sigma non-opioid intracellular receptor 1 ligand 1-methoxy-1'-... 1 1
Sigma non-opioid intracellular receptor 1 ligand SureCN7425449... 2 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324043 CHEMBL1172292 Bioactive (3R)-3-methoxy-1'-(4-phenylbutyl)spiro[3,4-dihydroisochromene-1,4'-piperidine]
CFAMM00324034 CHEMBL577956 Bioactive AGN-PC-076TWX
CFAMM00324040 CHEMBL2034985 Bioactive 3-methoxy-1'-octylspiro[3,4-dihydroisochromene-1,3'-pyrrolidine]
CFAMM00324038 CHEMBL570269 Bioactive AGN-PC-076TWY
CFAMM00324036 CHEMBL1171872 Bioactive (3R)-3-methoxy-1'-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]
CFAMM00324044 CHEMBL1172688 Bioactive SureCN8477144

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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