CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14784
Family Name Chitin synthase 1 inhibitor AC1O53V7 family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00430268 Functional Category Bioactive
Superfamily Chitin synthase 1 and Ferritin light chain Binder Superfamily
Class Class 664

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Amonafide family 3 35
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Transient receptor potential cation channel subfamily V member... 1 5
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Transient receptor potential cation channel subfamily V member... 1 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Chitin synthase 1 inhibitor AGN-PC-073JUR family 2 1
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 2 2
Proteinase-activated receptor 1 ligand 2-bromo-N-[3-(butanoyla... 4 0
Lysophosphatidic acid receptor 3 and Microtubule-associated pr... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430264 CHEMBL35895 Bioactive AC1LAP71
CFAMM00430270 CHEMBL443517 Bioactive 5-[[4-(3,3-dimethylbut-1-ynyl)phenyl]methyl-methylamino]-3,4-dihydro-1H-quinolin-2-one
CFAMM00430269 CHEMBL35735 Bioactive AC1O53AV
CFAMM00430268 CHEMBL285056 Bioactive AC1O53V7
CFAMM00430267 CHEMBL36409 Bioactive AC1LAP77
CFAMM00430266 CHEMBL36446 Bioactive AC1O53AP
CFAMM00430272 CHEMBL36240 Bioactive AC1O53AY
CFAMM00430265 CHEMBL36445 Bioactive AC1O53AS
CFAMM00430271 CHEMBL35760 Bioactive AC1O53AM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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