CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14798
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand 4-[2-[(3,4-difluorophenyl)methyl]-1,3-oxazol-4-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00425239 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Beta-3 adrenergic receptor ligand 4-[[4-(1-benzofuran-2-yl)-1,... 2 0
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Growth hormone secretagogue receptor type 1 ligand SureCN48012... 2 2
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 10 29
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 8 5
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430352 CHEMBL36609 Bioactive 4-[2-[(3,4-difluorophenoxy)methyl]-1,3-oxazol-4-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00430350 CHEMBL285520 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[2-[[4-(trifluoromethyl)phenyl]methyl]-1,3-oxazol-4-yl]benzenesulfonamide
CFAMM00430355 CHEMBL418234 Bioactive 4-[2-[(4-fluorophenyl)methyl]-1,3-oxazol-4-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27293 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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