CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1480
Family Name C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[(2,4-difluorophenyl)methyl]-1-prop-2-enylurea family
No. of Seeds 7 No. of Other Members 13
Family Centroid CFAMM00324078 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Binder Superfamily 6
Class Class 3377

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor Ligand SNAP-6201 Family 41 94
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 10
Melanocortin receptor 4 and Melanocortin receptor 3 ligand Sur... 6 53
C-C chemokine receptor type 5 ligand benzyl N-[1-[[(3S,4R)-1-(... 2 4
C-C chemokine receptor type 5 ligand (4-methoxyphenyl)methyl N... 2 2
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 1 0
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 3 1
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 1 16
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 5 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 10
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 0
Prothrombin inhibitor SureCN6924249 family 6 4
C-C chemokine receptor type 5 ligand (2R)-3-cyclopropyl-2-[(3S... 6 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 20 2
C-C chemokine receptor type 5 ligand AC1LAKN8 family 4 5
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324078 CHEMBL1172050 Bioactive 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[(2,4-difluorophenyl)methyl]-1-prop-2-enylurea
CFAMM00324071 CHEMBL1172045 Bioactive 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[(4-fluorophenyl)methyl]-1-prop-2-enylurea
CFAMM00324070 CHEMBL1222769 Bioactive SureCN4188314
CFAMM00324076 CHEMBL1172048 Bioactive SureCN4017888
CFAMM00324079 CHEMBL1172051 Bioactive 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[(3,4-difluorophenyl)methyl]-1-prop-2-enylurea
CFAMM00324058 CHEMBL1222772 Bioactive 1-allyl-1-[(1R,5S)-8-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxy-pyrrolidin-3-yl]methyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-[[4-(trifluoromethyl)phenyl]methyl]urea
CFAMM00324072 CHEMBL1172046 Bioactive 3-[(4-chlorophenyl)methyl]-1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-1-prop-2-enylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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