CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14816
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand 4-[5-[(4-fluorophenoxy)methyl]-1,2,4-oxadiazol-3-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00430228 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 6
Class Class 3789

Cousin Family NamesSeedsMembers
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Beta-3 adrenergic receptor ligand 4-[[4-(1-benzofuran-2-yl)-1,... 2 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 10 29
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 4


External ID

Functional Category

Molecule Name

CFAMM00430464 CHEMBL286231 Bioactive 4-[5-[(2-hydroxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00430469 CHEMBL33292 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[5-[[4-(trifluoromethoxy)phenyl]methyl]-1,2,4-oxadiazol-3-yl]benzenesulfonamide
CFAMM00430462 CHEMBL34406 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[5-[(4-methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl]benzenesulfonamide
CFAMM00430468 CHEMBL288550 Bioactive SureCN8078585
CFAMM00430467 CHEMBL32411 Bioactive 4-[5-[(3,4-difluorophenoxy)methyl]-1,2,4-oxadiazol-3-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00430466 CHEMBL287562 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[5-(naphthalen-2-yloxymethyl)-1,2,4-oxadiazol-3-yl]benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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