CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1482
Family Name C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[[4-(methylsulfamoyl)phenyl]methyl]-1-prop-2-enylurea family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00324083 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 and Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily
Class Class 3378

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 10
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 7 13
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 1 0
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 1 16
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 5 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20


External ID

Functional Category

Molecule Name

CFAMM00324084 CHEMBL1172053 Bioactive 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[[4-(dimethylsulfamoyl)phenyl]methyl]-1-prop-2-enylurea
CFAMM00324083 CHEMBL1172052 Bioactive 1-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-3-[[4-(methylsulfamoyl)phenyl]methyl]-1-prop-2-enylurea
CFAMM00324082 CHEMBL1222775 Bioactive 1-[(1R,5S)-8-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl]methyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-[[4-(methylsulfamoyl)phenyl]methyl]-1-prop-2-enylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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