CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14821
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor N-[4-[(1R)-1-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyridin-4-ylethyl]phenyl]-2,3,4,5,6-pentafluorobenzenesulfonamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00430485 Functional Category Bioactive
Superfamily and Menin Binder Superfamily
Class Class 198

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Apricoxib family 8 77
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
5-hydroxytryptamine receptor 6 ligand AGN-PC-075BWR family 1 1
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430485 CHEMBL286421 Bioactive N-[4-[(1R)-1-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyridin-4-ylethyl]phenyl]-2,3,4,5,6-pentafluorobenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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