CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14823
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor (1R,2S)-2-[[4-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazin-1-yl]methyl]-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-ol family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00430486 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily 13
Class Class 142

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Acolbifene family 10 115
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Choline kinase alpha Inhibitor Hemicholinium-3 Family 4 0
Oestrogen receptor and Tyrosine-protein phosphatase non-recept... 92 21
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Renin Inhibitor Ro-65-7219 Family 10 8
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sodium-dependent serotonin transporter and Alpha-2A adrenergic... 2 2
Estrogen receptor and Estrogen receptor beta ligand SureCN3115... 9 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00E... 7 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430486 CHEMBL286949 Bioactive (1R,2S)-2-[[4-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazin-1-yl]methyl]-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26823 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543