CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14836
Family Name Reverse transcriptase/RNaseH inhibitor 1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimethoxyphenyl)ethyl]urea family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00430540 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Huntingtin Binder Superfamily
Class Class 873

Cousin Family NamesSeedsMembers
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Reverse transcriptase Inhibitor PT-115 Family 7 19
Reverse transcriptase/RNaseH inhibitor 1-[2-(6-chloro-3-ethoxy... 7 5
Reverse transcriptase/RNaseH inhibitor 1-(5-cyanopyridin-2-yl)... 5 0
Reverse transcriptase/RNaseH inhibitor AC1MHDM5 family 2 0
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 2 7
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1


External ID

Functional Category

Molecule Name

CFAMM00430539 CHEMBL35729 Bioactive 1-(5-chloropyridin-2-yl)-3-[2-(3-ethoxy-2-fluoro-6-methoxyphenyl)ethyl]urea
CFAMM00430541 CHEMBL38341 Bioactive 1-(5-chloropyridin-2-yl)-3-[(1R,2R)-2-(2-fluoro-3,6-dimethoxyphenyl)cyclopropyl]urea
CFAMM00430540 CHEMBL287317 Bioactive 1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimethoxyphenyl)ethyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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