CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14837
Family Name Cannabinoid receptor 1 ligand AGN-PC-07R6QU family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00430543 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 Ligand Rimonabant Superfamily
Class Class 213

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Cannabinoid receptor 1 Ligand Rimonabant Family 20 260
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Poly [ADP-ribose] polymerase 1 Inhibitor MK-4827 Family 8 43
Cannabinoid receptor 1 Ligand TM38837 Family 20 15
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M8RE fa... 6 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 5-(2-... 6 83
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 2
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 34 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Cannabinoid receptor 1 ligand N-[1-[[(1R)-1-[4-(3-chloroindazo... 10 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Cannabinoid receptor 1 ligand SureCN4819820 family 11 5
Cannabinoid receptor 1 and Peroxisome proliferator-activated r... 2 5
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor 2-(6-chloronaphthalen-2-yl)-5-m... 2 0
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor SureCN8165148 family 4 0
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 3
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Metabotropic glutamate receptor 5 ligand 5-(4-chlorophenyl)-1,... 3 1
Coagulation factor X inhibitor ethyl (3R,4S)-3-[(3-chloro-1H-i... 5 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 1
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Neutrophil elastase and Chymotrypsinogen B inhibitor 1-(3-meth... 1 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 0
Mitogen-activated protein kinase 8 inhibitor 5-[(6-chloro-1-ox... 5 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Progesterone receptor ligand AGN-PC-00OK6G family 7 8
D(4) dopamine receptor and D(1A) dopamine receptor ligand 3-[[... 1 0
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 3 22
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07NHI2 family 4 1
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand SureCN3822127 family 5 0
Cannabinoid receptor 1 ligand 1-(2-chlorophenyl)-5-(4-chloroph... 2 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R6RT family 3 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R6UP family 2 0
Cannabinoid receptor 1 ligand AGN-PC-07R9T4 family 27 0
Cannabinoid receptor 1 ligand AGN-PC-07R61A family 1 0
Cannabinoid receptor 1 and Translocator protein ligand AGN-PC-... 1 9
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 0
Cyclin-dependent kinase 2 inhibitor N-[(4-chlorophenyl)carbamo... 7 2
Apoptosis regulator Bcl-2 and Bcl2-associated agonist of cell ... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430547 CHEMBL594526 Bioactive AGN-PC-07R6RD
CFAMM00430545 CHEMBL595234 Bioactive AGN-PC-04RJHW
CFAMM00430543 CHEMBL594280 Bioactive AGN-PC-07R6QU
CFAMM00430542 CHEMBL287353 Bioactive AGN-PC-073JW8

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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