CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14839
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor AGN-PC-023J4G family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00430553 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM103... 14 12
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
Arachidonate 5-lipoxygenase-activating protein inhibitor SureC... 8 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 3
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 18 39
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430554 CHEMBL39419 Bioactive 4-[3-[3-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]propoxy]-4-[(4-methylphenyl)methoxy]benzoyl]indol-1-yl]butanoic acid
CFAMM00430553 CHEMBL287716 Bioactive AGN-PC-023J4G
CFAMM00430552 CHEMBL289397 Bioactive 4-[3-[4-[(4-methylphenyl)methoxy]-3-[3-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]propoxy]benzoyl]indol-1-yl]butanoic acid
CFAMM00430558 CHEMBL40847 Bioactive 4-[3-[3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethoxy]-4-[(4-methylphenyl)methoxy]benzoyl]indol-1-yl]butanoic acid
CFAMM00430551 CHEMBL289613 Bioactive AGN-PC-023J4X
CFAMM00430557 CHEMBL41413 Bioactive AGN-PC-023J4P
CFAMM00430556 CHEMBL39559 Bioactive AGN-PC-023J4R

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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