CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14841
Family Name Scytalone dehydratase inhibitor (2R)-2-cyano-N-[(2R)-1-(2,3-difluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide family
No. of Seeds 15 No. of Other Members 0
Family Centroid CFAMM00430580 Functional Category Bioactive
Superfamily Scytalone dehydratase and Cannabinoid receptor 1 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 4
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21e family 6 7
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Scytalone dehydratase inhibitor (1R)-2,2-dichloro-1-ethyl-N-[(... 9 1
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0


External ID

Functional Category

Molecule Name

CFAMM00430579 CHEMBL287765 Bioactive AGN-PC-073NEH
CFAMM00430572 CHEMBL295019 Bioactive (2R)-2-cyano-N-[(2R)-1-(2-fluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430580 CHEMBL287764 Bioactive (2R)-2-cyano-N-[(2R)-1-(2,3-difluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430578 CHEMBL43852 Bioactive (2R)-2-cyano-N-[(2R)-1-(3-fluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430571 CHEMBL295533 Bioactive SureCN6331462
CFAMM00430577 CHEMBL44315 Bioactive (2R)-2-cyano-N-[(2S)-1-(2,5-difluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430585 CHEMBL38816 Bioactive (2S)-2-cyano-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430576 CHEMBL296235 Bioactive 2-cyano-2-cyclopropyl-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]acetamide
CFAMM00430584 CHEMBL38815 Bioactive (2R)-2-cyano-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430575 CHEMBL40742 Bioactive 2-cyano-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]-3-methylbutanamide
CFAMM00430583 CHEMBL40347 Bioactive (2R)-2-cyano-3,3-dimethyl-N-[(2R)-1-phenoxypropan-2-yl]butanamide
CFAMM00430574 CHEMBL40907 Bioactive (2R)-2-cyano-N-[1-(3-fluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430582 CHEMBL41419 Bioactive AGN-PC-073NBK
CFAMM00430573 CHEMBL42731 Bioactive 2-cyano-N-[(2R)-1-(4-fluorophenoxy)propan-2-yl]-3,3-dimethylbutanamide
CFAMM00430581 CHEMBL290279 Bioactive 2-cyano-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]butanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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