CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14849
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor 1-[3-(6-methoxynaphthalen-2-yl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]propan-1-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00430634 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine receptor 1D Ligand (+/-)-nantenine Superfamily
Class Class 2644

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Sigma non-opioid intracellular receptor 1 ligand opiate Dextro... 9 33
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
DNA-dependent protein kinase catalytic subunit Inhibitor 2-pyr... 2 2
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Sigma non-opioid intracellular receptor 1 and Mu-type opioid r... 7 5
Sodium-dependent dopamine transporter and Sodium-dependent ser... 4 1
Sodium-dependent dopamine transporter and Transporter inhibito... 5 1
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430634 CHEMBL39990 Bioactive 1-[3-(6-methoxynaphthalen-2-yl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]propan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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