CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1485
Family Name Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor ligand AGN-PC-0886HG family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00192357 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor Binder Superfamily 2
Class Class 3379

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Adenosine receptor A1 Ligand SLV320 Family 6 79
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Tyrosine kinase Inhibitor PKI166 Family 17 198
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... 4 0
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand SureCN5... 1 0
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 1 0


External ID

Functional Category

Molecule Name

CFAMM00324116 CHEMBL1172209 Bioactive AGN-PC-0886HI

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



89087 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543