CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14857
Family Name Substance-P receptor ligand 1-[3-(3,4-dichlorophenyl)-3-[2-(1'-methylspiro[3,4-dihydro-2H-isoquinoline-1,4'-piperidin-1-ium]-1'-yl)ethyl]piperidin-1-yl]-2-(3-propan-2-yloxyphenyl)ethanone;iodide family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00430679 Functional Category Bioactive
Superfamily Substance-P receptor Binder Superfamily 8
Class Class 1077

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Neuromedin-K receptor ligand AGN-PC-09QL9U family 1 3
Melanocortin receptor 4 ligand [(3R,4S)-4-(4-chlorophenyl)-1-p... 5 8
Substance-P receptor ligand AGN-PC-073LX9 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00430679 CHEMBL289727 Bioactive 1-[3-(3,4-dichlorophenyl)-3-[2-(1'-methylspiro[3,4-dihydro-2H-isoquinoline-1,4'-piperidin-1-ium]-1'-yl)ethyl]piperidin-1-yl]-2-(3-propan-2-yloxyphenyl)ethanone;iodide
CFAMM00430685 CHEMBL288123 Bioactive 1'-[2-[3-(3,4-dichlorophenyl)-1-[2-(3-propan-2-yloxyphenyl)acetyl]piperidin-3-yl]ethyl]-1'-methylspiro[2,4-dihydroisoquinoline-1,4'-piperidin-1-ium]-3-one;iodide
CFAMM00430678 CHEMBL38763 Bioactive SR 140333
CFAMM00430684 CHEMBL288600 Bioactive SureCN7561842
CFAMM00430683 CHEMBL39595 Bioactive AGN-PC-073M1Q

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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