CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14858
Family Name Folylpolyglutamate synthase, mitochondrial and Dihydrofolate reductase inhibitor AGN-PC-001TCG family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00430687 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 1 and Mitogen-activated protein kinase 3 Inhibitor Purvalanol Superfamily
Class Class 1173

Cousin Family NamesSeedsMembers
Folate receptor gamma Ligand Folic Acid Family 4 100
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Thymidylate synthase inhibitor (2S)-2-[[4-[(2-methyl-4-oxo-1,6... 15 107
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 11
Thymidylate synthase inhibitor AC1LABAB family 14 3
Thymidylate synthase inhibitor (2R)-2-[[(4S)-4-carboxy-4-[[4-[... 55 43
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 11
Thymidylate synthase inhibitor AC1LAB82 family 17 0
Thymidylate synthase inhibitor AC1LAB7Z family 8 3
Dihydrofolate reductase and Thymidylate synthase inhibitor 2-[... 10 5
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 3 14
Thymidylate synthase inhibitor (2S)-2-[[(4S)-4-carboxy-4-[[(4S... 7 11
Thymidylate synthase inhibitor AGN-PC-0757PM family 1 0
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 1
Dihydrofolate reductase inhibitor 2-[[4-[2-(2-amino-4-oxo-1,5,... 2 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Thymidylate synthase inhibitor SureCN6446340 family 2 1
Cationic trypsin and Prothrombin inhibitor 2-ketobenzothiazole... 1 3
Thymidylate synthase inhibitor (2S)-2-[[(4S)-4-carboxy-4-[[(4S... 1 7
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-(2-aminoethyl)pipe... 17 2
P2Y purinoceptor 12 inhibitor (4S)-4-[[6-[4-[2-(methylamino)-2... 51 8
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 1 0
Beta-secretase 1 inhibitor 3-[[(2R,3S)-3-[[(2S)-2-[[(2S)-2-[[(... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430687 CHEMBL38937 Bioactive AGN-PC-001TCG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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