CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14865
Family Name Mu-type opioid receptor and Kappa-type opioid receptor ligand 1-[[(3S)-2-[[(2R)-1-[(2-methoxyphenyl)methyl]pyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-phenylurea family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00309611 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 10
Class Class 1350

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Substance-K receptor Ligand MEN-14933 Family 13 154
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(2,4-difl... 3 26


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430759 CHEMBL41946 Bioactive 1-[[(3S)-2-[[(2R)-1-[(2-hydroxy-3-methoxyphenyl)methyl]pyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-phenylurea
CFAMM00430752 CHEMBL288468 Bioactive 1-[[(3S)-2-[[(2R)-1-[(2,3-dimethoxyphenyl)methyl]pyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-phenylurea
CFAMM00430755 CHEMBL39272 Bioactive 1-[[(3S)-2-[[(2R)-1-[(4-hydroxy-2-methoxyphenyl)methyl]pyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-phenylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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