CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14866
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00430762 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Growth hormone secretagogue receptor type 1 Binder Superfamily
Class Class 3079

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Penicillin binding protein Inhibitor Cefadroxil Family 5 17
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Plitidepsin family 15 5
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Vasopeptidase Inhibitor Fasidotril Family 3 7
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Integrin beta-1 and Integrin alpha-4 inhibitor (3S,6R,11R,14S)... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Dipeptidyl peptidase 4 and Seprase inhibitor (2R)-2-[4-[[[(2S)... 17 19
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-ethy... 7 1
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6453971 f... 3 4
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulf... 2 11
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 9
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430762 CHEMBL288474 Bioactive SureCN6429531
CFAMM00430761 CHEMBL43858 Bioactive (2S)-2-[[(2S)-1-methylsulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(pyrrolidine-1-carbonyloxy)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48707 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543