CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1488
Family Name Receptor-type tyrosine-protein kinase FLT3 and Vascular endothelial growth factor receptor 2 ligand 2,4-dimethyl-5-[(Z)-[6-[(4-methylphenyl)carbamoylamino]-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00324127 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 and Glycogen synthase kinase-3 beta Binder Superfamily 2
Class Class 3380

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 4
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
RAC-beta serine/threonine-protein kinase inhibitor SureCN57283... 2 0
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1
Glycogen synthase kinase 3 beta and Dual specificity tyrosine-... 1 6
8-carbamoyl-6,7,8,9-tetrahydro-5H-carbazole-1-carboxylate NP Z... 2 0


External ID

Functional Category

Molecule Name

CFAMM00324123 CHEMBL1173107 Bioactive 2,4-dimethyl-5-[(Z)-[2-oxo-6-(phenylcarbamoylamino)-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid
CFAMM00324127 CHEMBL1172420 Bioactive 2,4-dimethyl-5-[(Z)-[6-[(4-methylphenyl)carbamoylamino]-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid
CFAMM00324126 CHEMBL1172421 Bioactive 5-[(Z)-[6-[(4-chlorophenyl)carbamoylamino]-2-oxo-1H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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