CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14892
Family Name Sigma non-opioid intracellular receptor 1 ligand AGN-PC-073OMG family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00430915 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 7 Ligand 2-(2-bromophenoxy)-n,n-dimethylethanamine Superfamily
Class Class 2660

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Histamine H3 receptor Ligand 1-(3-(2-(3-methoxyphenoxy)ethoxy)... 3 9
Tyrosinase Inhibitor 1-(3-phenoxypropyl)-4-(piperidin-1-yl)pip... 2 13
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Sigma non-opioid intracellular receptor 1 ligand SureCN7450653... 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-078ZCU... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 3


External ID

Functional Category

Molecule Name

CFAMM00430917 CHEMBL289196 Bioactive AGN-PC-073OQA
CFAMM00430915 CHEMBL46880 Bioactive AGN-PC-073OMG
CFAMM00430914 CHEMBL45156 Bioactive 4-[(4-bromophenoxy)methyl]-1-(3-fluoropropyl)piperidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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