CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14896
Family Name Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ligand AGN-PC-073NOD family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00296802 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-phenyl)-1-methyl-piperidin-2-one Superfamily
Class Class 2042

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
DNA Binder Procarbazine Family 8 358
Mu-type opioid receptor Ligand Diphenoxylate Family 5 6
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Neuromedin-K receptor Ligand Osanetant Family 38 192
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor Bexlosteride... 5 23
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Sodium-dependent dopamine transporter and Transporter inhibito... 4 3
Substance-P receptor ligand AGN-PC-075NUD family 4 1
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Vasopressin V1a receptor ligand (2R)-3-(4-chlorophenyl)-2-[[2-... 6 2
Vasopressin V1a receptor ligand N-[(2R)-3-(4-chlorophenyl)-1-[... 6 0
Transporter and Sodium-dependent dopamine transporter inhibito... 6 1
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
C-C chemokine receptor type 5 ligand AGN-PC-075XOD family 2 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 7 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 4 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 6 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-2-... 6 0
Alpha-1A adrenergic receptor and Histamine H1 receptor ligand ... 13 1
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor methyl ... 6 2
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00430935 CHEMBL44294 Bioactive SureCN7967306

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543