CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14909
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand 4-(2-fluorophenyl)-2-(4-methylpiperazin-1-yl)-3-[2-(oxolan-2-yloxy)ethyl]quinoline family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00431029 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine receptor 3A Binder Superfamily 6
Class Class 2845

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431029 CHEMBL289664 Bioactive 4-(2-fluorophenyl)-2-(4-methylpiperazin-1-yl)-3-[2-(oxolan-2-yloxy)ethyl]quinoline
CFAMM00431028 CHEMBL42911 Bioactive 2-(4-methylpiperazin-1-yl)-3-[2-(oxolan-2-yloxy)ethyl]-4-phenylquinoline
CFAMM00431027 CHEMBL289732 Bioactive 2-(4-methylpiperazin-1-yl)-3-(oxolan-2-yloxymethyl)-4-phenylquinoline
CFAMM00431026 CHEMBL290065 Bioactive 4-(2-fluorophenyl)-2-(4-methylpiperazin-1-yl)-3-[2-(oxan-2-yloxy)ethyl]quinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48713 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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