CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1492
Family Name Aldo-keto reductase family 1 member B10 and Aldose reductase inhibitor 2-(4-hydroxyanilino)-7-oxo-N-pyridin-2-ylchromene-3-carboxamide family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00324165 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Aldose reductase Binder Superfamily 3
Class Class 1612

Cousin Family NamesSeedsMembers
Glucokinase Inhibitor GKA1 Family 2 67
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Histamine H1 receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5... 3 10
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5735477 f... 1 1
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0


External ID

Functional Category

Molecule Name

CFAMM00324166 CHEMBL2440423 Bioactive 4-[[7-oxo-3-(pyridin-2-ylcarbamoyl)chromen-2-yl]amino]benzoic acid
CFAMM00324165 CHEMBL2440422 Bioactive 2-(4-hydroxyanilino)-7-oxo-N-pyridin-2-ylchromene-3-carboxamide
CFAMM00324160 CHEMBL1172665 Bioactive STK074083
CFAMM00324169 CHEMBL2440424 Bioactive 2-(4-methylanilino)-7-oxo-N-pyridin-2-ylchromene-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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