CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14921
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-073MH3 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00431106 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta Inhibitor A-313326 Superfamily
Class Class 2754

Cousin Family NamesSeedsMembers
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Extracellular calcium-sensing receptor ligand SureCN2972008 fa... 4 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 19 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 21 0
Translocator protein inhibitor SureCN6906757 family 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
Malonyl-CoA decarboxylase, mitochondrial inhibitor AGN-PC-075Z... 5 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431105 CHEMBL43082 Bioactive SureCN5099555
CFAMM00431106 CHEMBL290161 Bioactive AGN-PC-073MH3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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