CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14934
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand SureCN8088116 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00431154 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor Ligand Losartan Superfamily
Class Class 306

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 37
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Purine nucleoside phosphorylase inhibitor 7-[(3R,4S,5R)-3,4-di... 10 34
Purine nucleoside phosphorylase inhibitor 2-amino-7-[[(2S,4R)-... 5 0
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Type-1B angiotensin II receptor ligand lithium;[2-butyl-5-chlo... 1 2
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 1-... 8 6
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
cGMP-dependent 3',5'-cyclic phosphodiesterase inhibitor SureCN... 4 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Purine nucleoside phosphorylase inhibitor SureCN6345422 family 9 11
Purine nucleoside phosphorylase inhibitor (3s)-3-(2-amino-4-hy... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1 angiotensin II receptor ligand AGN-PC-00FH82 family 1 1
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Purine nucleoside phosphorylase inhibitor SureCN6353628 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431156 CHEMBL290907 Bioactive 2-cyclopropyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5H-imidazo[4,5-c]pyridin-4-one
CFAMM00431155 CHEMBL45102 Bioactive 2-ethyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5H-imidazo[4,5-c]pyridin-4-one
CFAMM00431154 CHEMBL429008 Bioactive SureCN8088116
CFAMM00431158 CHEMBL46822 Bioactive 2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5H-imidazo[4,5-c]pyridin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543