CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14935
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand AGN-PC-002MNO family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00431159 Functional Category Bioactive
Superfamily Scavenger receptor class B member 1 and 5-hydroxytryptamine receptor 3B Binder Superfamily
Class Class 920

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Translocator protein Inhibitor Emapunil Family 7 89
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 3
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Sonic hedgehog protein and Smoothened homolog inhibitor N-(4,4... 2 13
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2833591 f... 4 6
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[[3-(2-aminoet... 8 7
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 3-[3-... 4 9
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-077MAQ fa... 1 0


External ID

Functional Category

Molecule Name

CFAMM00431159 CHEMBL291031 Bioactive AGN-PC-002MNO

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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